This course provides fundamental knowledge about piezoelectric materials from device to systems. Different perspectives from viewpoint of mechanical engineers, electrical engineers and material engineers will also be examined. Smart structures based on piezoelectric materials will serve as an initial platform to examine the pros and cons of using distributed sensors and point sensors. The design concept, performance specifications, and application know-how will be examined for both sensors and actuators. Simple control theories will be briefly introduced to understand the fundamental requirements of sensors within a control loop. Both theoretical framework and experimental implementations will be discussed. Different scenarios based on various applications will be used to provide the background, implementation details, and design considerations of the schematics.